Chromatographic separation technology is based on the fact that different substances have different partition coefficients in a system composed of a stationary phase and a mobile phase, and exhibit different retention times in the mobile phase elution process, thereby achieving separation.
At present, the simulated moving bed continuous chromatographic separation technology has achieved mature industrialization. The main principle is to use a solenoid valve group to simulate the effect of the actual switching of the resin column in the moving bed. Open and close when feeding and discharging to the corresponding resin column.
Similar to the principle of tortoise and rabbit race, we must make the stationary phase into a conveyor belt, and separate the rabbit and turtle into two components with different speeds. As long as the stationary phase is added with a driving force opposite to the elution direction, the conveyor belt moves at a speed In the middle of the speed between the rabbit and the turtle, the faster-running rabbit is obtained from the front faster than the stationary phase, and the slow-running turtle is obtained by the conveyor belt.
Separation of fructose to produce crystalline fructose
Xylitol / Arabinose
Glucose or maltose / high sugar
Mannitol / sorbitol